Status:
UNKNOWN
Euthyroid Sick Syndrome (ESS) Effect on Traumatic Brain Injury Patients and Its Relation With GFAP Level
Lead Sponsor:
Minia University
Conditions:
Euthyroid Sick Syndromes in Traumatic Brain Injury Patient and GFAP Level
Eligibility:
All Genders
18-60 years
Brief Summary
Euthyroid sick syndrome (ESS) effects on patients suffering from traumatic brain injury (TBI) have received little attention. Moreover, there is limited evidence that serum levels of thyroid-related h...
Detailed Description
After obtaining the approval of research ethical committee of faculty of medicine ,El-Minia university and taking informed written consent from the participants or their relatives, this prospective cr...
Eligibility Criteria
Inclusion
- Age : between (18-60) years old.
- Gender : both males and females.
- Isolated moderate to severe traumatic brain injury(TBI) GCS (3-12) who is expected to survive for more than 24 hours
Exclusion
- Poly trauma patients.
- Critically ill patients.
- Patients with history of endocrinal disturbance involving both hypothalamo-pituitary axis and thyroid gland.
- Patients receiving antithyroid medication or hormonal replacement like thyroxin and insulin.
- Pregnant and lactating females.
- Patients with history neurological or psychiatric disorders.
- Patients with liver or renal failure.
- Patients with recent use of amiodarone or β-blockers.
Key Trial Info
Start Date :
September 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 30 2022
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT04806672
Start Date
September 1 2022
End Date
December 30 2022
Last Update
August 24 2022
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