Status:

UNKNOWN

PRP Effectiveness in Knee Osteoarthritis

Lead Sponsor:

Istanbul University

Conditions:

Knee Osteoarthritis

Eligibility:

All Genders

30-75 years

Phase:

NA

Brief Summary

The aim of our study is to determine the effects of intra-articular Platelet Rich Plasma (PRP) prepared with two different techniques on pain intensity, functional status, quality of life, functional ...

Detailed Description

Osteoarthritis (OA) is the most common form of chronic joint disease. Platelet Rich Plasma (PRP) is an injection therapy used to treat chronic painful musculoskeletal conditions, including knee OA. In...

Eligibility Criteria

Inclusion

  • Patients with chronic symptomatic knee pain between the ages of 30-75 years
  • Presence of Kellgren-Lawrence stage 2-3 osteoarthritis on current anterior-posterior knee radiographs
  • Functional ambulation scale stage 4-5

Exclusion

  • Intra-articular knee injection within the last six months
  • History of severe trauma to the knee within the past six months
  • Concomitant severe meniscus or ligament injury, surgery applied to the knee area
  • Presence of severe effusion, inflammatory joint disease, infection, hematological and oncological disease in the knee.
  • Having a bleeding disorder and / or using warfarin
  • Kellgren-Lawrence stage 1 or stage 4 osteoarthritis on current anterior-posterior knee radiographs
  • Presence of cardiac or systemic disease that may affect exercise
  • The presence of neurological disease and psychiatric disease such as Parkinson's disease, stroke history that may affect balance
  • Body Mass Index ≥35 kg / m²

Key Trial Info

Start Date :

March 22 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2021

Estimated Enrollment :

75 Patients enrolled

Trial Details

Trial ID

NCT04807270

Start Date

March 22 2021

End Date

December 1 2021

Last Update

March 19 2021

Active Locations (1)

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Istanbul University Istanbul Faculty of Medicine, Department of Physical Medicine and Rehabilitation

Istanbul, Fatıh, Turkey (Türkiye), 34034