Status:
UNKNOWN
Role of Intravenous Lipid Emulsion in Improving Coma of Acute Antipsychotics Poisoning
Lead Sponsor:
Ain Shams University
Conditions:
Coma
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Intravenous Lipid Emulsion in Improving Coma Of Antipsychotic drugs Acute Poisoning: A Randomized Controlled Trial in Poison Control Center of Ain Shams University Hospitals
Detailed Description
Intravenous lipid emulsions (ILEs) have been recently used in treatment of acute toxicity caused by lipophilic drugs including local anesthetics, antidepressants, anti-arrhythmics, beta blockers and c...
Eligibility Criteria
Inclusion
- All adult comatose patients admitted to the ICU of Poison Control Center of Ain Shams University Hospitals with positive history of antisychotic drugs overdose during the period starting from the beginning of March 2020 to the end of Septemper 2021
Exclusion
- Based on the possibility of heterogeneity in hemodynamic parameters, laboratory variables, GCS and/or AVPU Scale, the following patients will be excluded:
- Patients less than 18 years and more than 65 years.
- Pregnant and lactating females.
- Co-ingestion of other agents.
- Presence of medical diseases (e.g. renal, hepatic, cardiovascular diseases) and chronic pancreatitis.
- History of head trauma.
- Presence of conditions where ILE is contraindicated.
Key Trial Info
Start Date :
March 10 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2021
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT04807634
Start Date
March 10 2021
End Date
September 1 2021
Last Update
March 19 2021
Active Locations (1)
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1
Hend salama shalby El Far
Cairo, Egypt