Status:
NOT_YET_RECRUITING
LIA vs. LIA + ACB-iPACK Block for Total Knee Arthroplasty
Lead Sponsor:
Women's College Hospital
Conditions:
Nerve Block
Neuromuscular Blockade
Eligibility:
All Genders
18-85 years
Phase:
NA
Brief Summary
LIA is the mainstay of postoperative analgesia in patients having knee arthroplasty. The combination of ACB-iPACK blocks has also been proposed as an effective analgesic modality for total knee arthro...
Detailed Description
LIA is the mainstay of postoperative analgesia in patients having knee arthroplasty. Performed by surgeons, LIA provides effective postoperative pain relief and reduces opioid requirements. Similar an...
Eligibility Criteria
Inclusion
- ASA classification I-III
- BMI \< 35 kg/m2
- Having elective unilateral total knee arthroplasty
Exclusion
- Bilateral knee surgery.
- Pre-existing neurological deficit or peripheral neuropathy in the lower the lower limbs
- Severe, poorly controlled cardiac conditions, significant arrhythmias, severe valvular heart diseases
- Severe, poorly controlled respiratory conditions (severe COPD, severe interstitial lung disease, severe / poorly controlled asthma)
- Contraindication to regional anesthesia (e.g. bleeding diathesis, coagulopathy, sepsis, infection at the site of potential needle puncture on the posterior chest)
- Patient refusal
- Chronic pain disorder
- Chronic opioid use (≥30 mg oxycodone / day)
- Contraindication (or allergy) to a component of multi-modal analgesia protocol
- Allergy to amide local anesthetics used in nerve blocks
- Contraindications to spinal anesthesia
- Significant psychiatric disorder that would preclude objective study assessment
- Pregnancy
- Inability to provide informed consent
Key Trial Info
Start Date :
January 1 2027
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2028
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT04808947
Start Date
January 1 2027
End Date
December 1 2028
Last Update
July 16 2025
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.