Status:
COMPLETED
Nutraceutical Composition Containing Natural Products Derivatives on the Modulation of the Endocrine Neuroimmune Axis
Lead Sponsor:
University of Sao Paulo General Hospital
Collaborating Sponsors:
University of Sao Paulo
Conditions:
Insulin Resistance
Inflammatory Bowel Diseases
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The use of natural products in the prevention or treatment of chronic diseases is an emerging field in current medicine. And studying the mechanisms of actions by which natural products act in our bod...
Detailed Description
Obesity and diabetes are chronic diseases characterized by increased visceral adipose tissue and sub-acute inflammation. These conditions can lead to insulin resistance, hyperglycemia, oxidative stres...
Eligibility Criteria
Inclusion
- Healthy (healthy) and sedentary volunteers: people without chronic use of drugs for chronic inflammatory diseases that require the use of corticosteroids or NSAIDs (Non-Steroidal Anti-inflammatories) for a period of more than 15 days. BMI (Body Mass Index) of 24.9 Kg / m2.
- Sedentary overweight/obesity grade 1 volunteer: overweight people, with a BMI of 25.0 to 29.9 kg / m2; and grade 1 obesity with a BMI of 30.0 and 34.9 kg / m2, with or without dyslipidemia and/or non-insulin-dependent type 2 diabetics.
Exclusion
- Volunteers who are allergic to some of the components of the nutraceutical formulation, who use insulin, corticosteroids, and NSAIDs for more than 15 days, AIDS, hepatitis, patients undergoing chemotherapy.
Key Trial Info
Start Date :
May 20 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 19 2022
Estimated Enrollment :
162 Patients enrolled
Trial Details
Trial ID
NCT04810572
Start Date
May 20 2021
End Date
December 19 2022
Last Update
February 1 2024
Active Locations (1)
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1
USP Medical School
São Paulo, Brazil, 01246 903