Status:

COMPLETED

The Role of Spectral Filtering in a Spectrally Adjustable Ocular Photosensitivity Analyzer

Lead Sponsor:

Johnson & Johnson Vision Care, Inc.

Conditions:

Photosensitivity

Eligibility:

All Genders

18-30 years

Phase:

NA

Brief Summary

This is a 6-visit, single-center, non-dispensing, randomized, single-masked, 5×5 crossover study. Subjects will participate in 6 scheduled over the duration of approximately 10.5 months.

Eligibility Criteria

Inclusion

  • Potential subjects must satisfy all of the following criteria to be enrolled in the study:
  • The subject must read and sign the Informed Consent form.
  • The subject must appear able and willing to adhere to the instructions set forth in this clinical protocol.
  • Healthy adult males or females age ≥18 and ≤30 years of age.
  • Normal color vision as measured using the Ishihara 38-plate test.
  • Normal stereopsis as measured by a suitable test.
  • Auto-refraction must show a spherical component of -2.00 through +2.00 D, and a cylindrical component of 0.00 through 1.50 D.
  • The subject's distance refractive sphere must be between -2.00 and +2.00 D in each eye.
  • The subject's distance refractive cylinder must be ≤ 1.50 D in each eye.
  • The subject must have unaided distance Snellen visual acuity of 20/200 or better for each eye.
  • The subject must have best corrected distance Snellen visual acuity of 20/25 or better for each eye.

Exclusion

  • Potential subjects who meet any of the following criteria will be excluded from participating in the study:
  • Currently pregnant or lactating (subjects who become pregnant during the study will be discontinued).
  • History of refractive surgery or other ocular surgery.
  • Employee or immediate family member of an employee of clinical site (e.g., Investigator, Coordinator, Technician).
  • Subjects that participated in the pilot study CR-6318.
  • Systemic conditions or the use of medications that the investigator believes will contraindicate participation in this study.
  • Abnormal Level 3 neuro-ophthalmology exam including crystalline lens clarity Grade 3 or worse (Lens Opacities Classification System).
  • Any Grade 3 or greater slit lamp findings (e.g., edema, corneal neovascularization, corneal staining, tarsal abnormalities, conjunctival injection) on the FDA Slit Lamp Classification Scale.

Key Trial Info

Start Date :

July 14 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 16 2022

Estimated Enrollment :

53 Patients enrolled

Trial Details

Trial ID

NCT04811079

Start Date

July 14 2021

End Date

May 16 2022

Last Update

April 25 2025

Active Locations (1)

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University of Miami Health - Bascom Palmer Eye Institute

Coral Gables, Florida, United States, 33146