Status:
COMPLETED
Magnesium Sulfate for Analgesia in Pediatric Transplant
Lead Sponsor:
University of Minnesota
Conditions:
Postoperative Pain
Eligibility:
All Genders
3-18 years
Phase:
PHASE2
Brief Summary
To use magnesium sulfate as adjuvant analgesia by implementing a treatment protocol in order to determine whether can benefit pediatric pain in post-operative transplanted patients and decrease overal...
Detailed Description
The post-operative ICU course for children receiving liver transplants and TPIAT (total pancreatectomy with islet cell autotransplantation) includes a number of different challenges, one of which incl...
Eligibility Criteria
Inclusion
- Experimental Group:
- \- Be scheduled for and receive a liver transplant or total pancreatectomy and islet cell autotransplantation
- Control Group:
- \- Received a liver transplant or total pancreatectomy and islet cell autotransplantation.
Exclusion
- Experimental Group:
- Pregnant or unwilling to abstain from sex if not practicing birth control during participation in the study.
- Presence of a condition or abnormality that in the opinion of the Investigator would compromise the safety of the patient or the quality of the data.
- Known allergic reactions to components of the MgSO4
- History of heart block or myasthenia graves in past medical history.
- Presence of cardiac pacemaker
- Any patient with preoperative creatinine level \> 1.5x upper limit of normal.
- Control Group:
- Any patient who had filed as research-exempt (opt-out of research previously).
- Any patient with preoperative creatinine level \> 1.5x upper limit of normal.
Key Trial Info
Start Date :
March 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 10 2023
Estimated Enrollment :
66 Patients enrolled
Trial Details
Trial ID
NCT04812028
Start Date
March 1 2021
End Date
August 10 2023
Last Update
October 28 2024
Active Locations (1)
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1
University of Minnesota
Minneapolis, Minnesota, United States, 55455