Status:
COMPLETED
Healing of Apical periodontitis-the Effect of Diabetes Mellitus and Tobacco Smoking
Lead Sponsor:
Romana Peršić Bukmir
Collaborating Sponsors:
University of Rijeka
Conditions:
Periapical Periodontitis
Eligibility:
All Genders
18-75 years
Brief Summary
Apical periodontitis is an inflammatory process located around the apex of the root. It is mainly caused by a microbial infection of the pulp space. Diabetes mellitus and tobacco smoking are modulatin...
Detailed Description
Apical periodontitis is an inflammatory process located around the apex of the root. It is mainly caused by a microbial infection of the pulp space. Diabetes mellitus and tobacco smoking are modulatin...
Eligibility Criteria
Inclusion
- Inclusion Criteria
- Influence of smoking habit on apical periodontitis healing after non-surgical endodontic treatment
- Smoker group- everyday cigarette smoking habit, older than 18 years
- Control group-healthy non-smoker patients, older than 18 years, paired with smoker group according to age and sex
- Influence of diabetes mellitus on apical periodontitis healing after non-surgical endodontic treatment
- Diabetic group-patients having type 2 diabetes mellitus, older than 18 years, non-smokers
- Control group-healthy patients, non-smokers, older than 18 years, paired with diabetic group according to age and sex
- Exclusion Criteria:
- Influence of smoking habit on apical periodontitis healing after non-surgical endodontic treatment
- Smoker group-systemic disease, pregnancy, taking medications that interfere with bone metabolism and immunologic response, former and occasional smokers
- Control group-former, occasional and present smokers,systemic disease, pregnancy, taking medications that interfere with bone metabolism and immunologic response
- Influence of diabetes mellitus on apical periodontitis healing after non-surgical endodontic treatment Diabetic group-pregnancy, taking medications that interfere with bone metabolism and immunologic response, smokers Control group-patients having diabetes mellitus, pregnancy, taking medications that interfere with bone metabolism and immunologic response, smokers
Exclusion
Key Trial Info
Start Date :
April 1 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 3 2023
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT04812171
Start Date
April 1 2021
End Date
July 3 2023
Last Update
July 5 2023
Active Locations (1)
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1
University of Rijeka Faculty of Dental Medicine
Rijeka, Croatia, 51000