Status:

COMPLETED

Dietary Fat and Endothelial Function in Type 1 Diabetes

Lead Sponsor:

University Magna Graecia

Conditions:

Type 1 Diabetes

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of this study is to evaluate the effects of the add-on of extra vergin olive oil or butter to a high glycemic index meal on endothelial function in subjects with type 1 Diabetes and health...

Detailed Description

Impaired endothelial function is an early manifestation of atherosclerosis and predictor of incident cardiovascular events. Diabetes affects arterial vasodilation by reducing the bioavailability of NO...

Eligibility Criteria

Inclusion

  • age ≥ 18 years,
  • diagnosis of type 1 diabetes since at least 1 year,
  • HbA1c \<8.5% (69 mmol/mol),
  • stable insulin therapy for at least 3 months before the enrolment into the study

Exclusion

  • pregnancy, celiac disease, history of cardiovascular diseases, hypertension, hyperlipidemia, retinopathy, nephropathy, neuropathy, and ongoing treatment with vasoactive drugs.

Key Trial Info

Start Date :

February 12 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 16 2019

Estimated Enrollment :

16 Patients enrolled

Trial Details

Trial ID

NCT04812782

Start Date

February 12 2018

End Date

October 16 2019

Last Update

March 24 2021

Active Locations (1)

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University Magna Graecia

Catanzaro, Italy, 88100