Status:

COMPLETED

Pilot Study of Sex-matched vs. Sex-mismatched Red Blood Cell Transfusion

Lead Sponsor:

McMaster University

Collaborating Sponsors:

Canadian Institutes of Health Research (CIHR)

Conditions:

Blood Transfusion

Eligibility:

All Genders

18+ years

Phase:

EARLY_PHASE1

Brief Summary

Blood transfusion is common for patients in hospital, especially for those in intensive care. Patients receive blood that is matched to them based on their blood group (A, B, AB, O), but not based on ...

Detailed Description

Blood transfusion is one of the most common procedures performed during hospitalization. Approximately 85 million red blood cell (RBC) units are transfused globally each year. RBC units are matched fo...

Eligibility Criteria

Inclusion

  • Adults (age ≥18)
  • Admitted to the intensive care unit
  • Requiring a red blood cell transfusion

Exclusion

  • Requiring a specific red blood cell unit or unit not readily available (e.g., phenotypically matched, rare blood, washed, complex red blood cell antibodies, etc.)
  • Massively bleeding (i.e. ≥4 units of blood ordered, or Massive Hemorrhage Protocol initiated, or an urgent blood request made)
  • Biological sex unknown

Key Trial Info

Start Date :

January 7 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 28 2023

Estimated Enrollment :

270 Patients enrolled

Trial Details

Trial ID

NCT04814264

Start Date

January 7 2022

End Date

February 28 2023

Last Update

March 16 2023

Active Locations (5)

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Page 1 of 2 (5 locations)

1

Hamilton General Hospital

Hamilton, Ontario, Canada, L8L 2X2

2

St. Joseph's Healthcare Hamilton

Hamilton, Ontario, Canada, L8N 4A6

3

Kingston Health Sciences Centre

Kingston, Ontario, Canada, K7L 2V7

4

London Health Sciences Centre

London, Ontario, Canada, N6A 5W9