Status:
UNKNOWN
Role of Neoadjuvent Radiotherapy in Locally Advanced Cancer Rectum
Lead Sponsor:
Amany sayed Abass
Conditions:
Rectal Adenocarcinoma
Eligibility:
All Genders
18-70 years
Brief Summary
This is a retrospective study comparing neoadjuvent short course radiotherapy to conventional chemoradiation in locally advanced cancer rectum and the effect of both regimens in overall survival and d...
Detailed Description
Colorectal cancer is the third most common cancer diagnosed in the western world. In 2019 there were approximately 44180 new cases of rectal cancer diagnosed in the United states. Due to the close pr...
Eligibility Criteria
Inclusion
- histologically proved adenocarcinoma of the rectum
- Age between 18 and 70 yrs
- T3 and T4 N1,N2 respectable tumor
- The WHO performance score 0-2
- have a free metastatic work up excluded by chest x-ray , abdominal ultrasonography or CT pelviabdomen
Exclusion
- patients with locally advanced inoperable disease locally recurrent rectal cancer
- had a history of malignant tumor within 5 years except the skin cancer
- pregnant or lactating women
- previous irradiation in pelvis
- there was contraindication for neoadjuvent radiotherapy or surgery
- known metastatic disease
- mental disorder
Key Trial Info
Start Date :
March 31 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2022
Estimated Enrollment :
48 Patients enrolled
Trial Details
Trial ID
NCT04814784
Start Date
March 31 2021
End Date
October 1 2022
Last Update
March 24 2021
Active Locations (1)
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1
South Egypt cancer Institute
Asyut, Egypt