Status:
RECRUITING
Electroacupuncture to Assist Ventilator Weaning in Severe Stroke
Lead Sponsor:
The Second Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine
Conditions:
Severe Stroke
Electroacupuncture
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
The purpose of this study is to evaluate the efficacy of electroacupuncture in assisting ventilator weaning in patients with severe stroke
Detailed Description
Disuse atrophy of the major respiratory muscles and diaphragmatic dysfunction often develop during mechanical ventilation, and cause difficulties in ventilator weaning. Electroacupuncture was indicate...
Eligibility Criteria
Inclusion
- age ≥ 18 years and ≤ 75 years ;
- within 7 days after the onset of stroke (ischemic or hemorrhagic), confirmed by a computed tomography (CT) or magnetic resonance imaging (MRI) scan of the brain;
- GCS on admission ≤ 12 or NIHSS on admission ≥ 11 or APACHEⅡ ≥ 15;
- received mechanical ventilation;
- written informed consent is able to be obtained directly from the patient or an appropriate surrogate, based on local ethics committee recommendations.
Exclusion
- expected to be ventilated for \< 24 h;
- already ventilated for \> 72 h;
- GCS \<5;
- with unstable vital signs and requiring the use of vasoactive agents;
- concomitant medical illness that would interfere with the outcome assessments and/or follow-up;
- had spinal cord injury above T8 level, or lower motor neuron impairment, or neuromuscular junction impairment，or chest wall deformities, or chest wall injuries within 6 months, or chest or abdominal surgery within 4 week, or were pregnant;
- had acute skin injury on the selected acupoints;
- currently participating in other investigational trials.
Key Trial Info
Start Date :
April 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04816201
Start Date
April 1 2021
End Date
December 1 2025
Last Update
May 22 2024
Active Locations (1)
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1
The Second Affiliated Hospital of Guangzhou University of Chinese Medicine
Guangzhou, Guangdong, China, 510120