Status:
COMPLETED
Boosting the Impact of SMC Through Simultaneous Screening and Treatment of Roommates
Lead Sponsor:
Institut de Recherche en Sciences de la Sante, Burkina Faso
Conditions:
Malaria
Malaria Prophylaxis
Eligibility:
All Genders
Phase:
PHASE4
Brief Summary
Malaria represents a major public health concern in sub-Sahara Africa. Seasonal malaria chemoprevention (SMC) is one of the largest preventive measures. It consists to administer Amodiaquine+Sulfadoxi...
Detailed Description
Malaria represents a major public health concern in sub-Sahara Africa. According to the World Health Organization (WHO) nearly half of the world's population is exposed to malaria infection causing 40...
Eligibility Criteria
Inclusion
- Single household (not sharing the same concession with other households) with children under SMC coverage (aged 3-59 months) with at least one child under 35 months of age,
- Household members residing within the HDSS catchment area,
- Willingness of roommates to be screened and treated,
- Ability to complete the study follow-up period,
- Written consent obtained from parents/guardian
- Written consent/assent obtained from roommates
Exclusion
- Household with children under SMC coverage who did not receive the SMC (Amodiaquine-Sulfadoxine-Pyrimethamine) or sharing the same concession with other households
- Household with children under SMC coverage but at least one of his/her roommates refuse to be screened and treated (these children will still receive the SMC treatment as part of their routine malaria prevention policy)
- Severely ill individual at the time of enrolment including severe malaria,
- Known allergy to AQSP for children and DHAPPQ for roommates
- Planned travel or inability to complete the study follow-up,
- Participation to malaria vaccine trial
- Unwillingness to participate to the study.
Key Trial Info
Start Date :
July 7 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 30 2023
Estimated Enrollment :
526 Patients enrolled
Trial Details
Trial ID
NCT04816461
Start Date
July 7 2021
End Date
June 30 2023
Last Update
January 22 2025
Active Locations (1)
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1
Institut de Recherche en Sciences de la Santé/ Clinical Research Unit of Nanoro
Nanoro, Boulkiemdé, Burkina Faso, 18 campus urcn