Status:

UNKNOWN

Seroprevalence of Neutralizing Antibodies Against Japanese Encephalitis Virus Among 6 Years Old Children With 5 Different Immunization Strategies in Zhejiang Province

Lead Sponsor:

Zhejiang Provincial Center for Disease Control and Prevention

Collaborating Sponsors:

Liaoning Chengda Biotechnology CO., LTD

Conditions:

Japanese Encephalitis

Vaccine Preventable Disease

Eligibility:

All Genders

72-75 years

Phase:

PHASE4

Brief Summary

This study is to evaluate the seroprevalence of neutralizing antibodies against Japanese encephalitis (JE) virus in children aged 6 years who were previously administered with 5 different immunization...

Detailed Description

Based on the retrospective registry in Zhejiang Provincial Immunization Information System, healthy children aged 6 years from 5 cohorts were included according to their previous immunization schedule...

Eligibility Criteria

Inclusion

  • Participants aged ≥ 72 months to \< 75 months.
  • Participants have completed routine immunization schedules in time.
  • Participants are healthy native residents.
  • Parents/guardians can understand the protocol requirements, provide informed consent, accept all scheduled visits, and comply with all trial procedures.

Exclusion

  • History of neurological diseases or related symptoms.
  • An acute illness with fever (temperature ≥ 37.1℃) or any acute onset of chronic diseases.
  • Known impairment of immunologic function, or receipt of immunosuppressive therapy or immunoglobulin in the past 3 months.
  • Known allergy to any constituent of the vaccine.
  • Have been injected with other vaccines or any clinical trial drugs in the past 4 weeks.
  • Any condition which, in the opinion of the investigator, would pose a health risk to the subject or interfere with the vaccine.

Key Trial Info

Start Date :

March 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 30 2023

Estimated Enrollment :

712 Patients enrolled

Trial Details

Trial ID

NCT04817917

Start Date

March 1 2021

End Date

June 30 2023

Last Update

November 15 2022

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Liandu center for disease control and prevention

Lishui, Zhejiang, China, 323000

2

Kecheng center for disease control and prevention

Quzhou, Zhejiang, China, 324000

3

Pingyang center for disease control and prevention

Wenzhou, Zhejiang, China, 325400