Status:
COMPLETED
Does Perineural Dexamethasone Increase the Duration of an Ulnar Nerve Block When Controlling for Systemic Effects?
Lead Sponsor:
Zealand University Hospital
Conditions:
Anesthesia, Local
Eligibility:
All Genders
18-65 years
Phase:
PHASE2
Brief Summary
Investigators will assess if perineural dexamethasone can increase the duration of an ulnar nerve block when controlling for systemic effects in healthy volunteers.
Detailed Description
Healthy volunteers will have bilateral ulnar nerve blocks performed with bupivacaine on two different days with a minimum of 14 days wash-out. On one day, the participants will also receive dexamethas...
Eligibility Criteria
Inclusion
- Age of 18 years or above
- Must fully understand the protocol and sign written informed consent
- American Society of Anaesthesiologists Physical Status Classification System of 1 or 2
- Body Mass Index above 18 kg/m\^2
- For fertile women, safe contraceptives for the last month and negative urine human chorionic gonadotropin is required
Exclusion
- Participants unable to cooperate
- Participants unable to speak or read Danish
- Age above 65 years
- Cardiovascular disease
- Allergy to study medication
- History of alcohol or substance abuse
- Intake of corticosteroids within the last 14 days
- Daily intake of prescription analgesia within the last four weeks
- Intake of over-the-counter analgesia within the last 48 hours
- Neuromuscular diseases or wounds on the arms or hands preventing adequate test or block performance.
- Diabetes mellitus
Key Trial Info
Start Date :
April 7 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 15 2021
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT04817982
Start Date
April 7 2021
End Date
May 15 2021
Last Update
July 1 2021
Active Locations (1)
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1
Zealand University Hospital
Køge, Zealand Region of Denmark, Denmark, 4600