Status:

COMPLETED

Circulating Cancer Cells/Macrophage HYbrid Cells in Patients With Breast Cancer.

Lead Sponsor:

Institut Claudius Regaud

Conditions:

Breast Cancer

Eligibility:

FEMALE

18+ years

Phase:

NA

Brief Summary

Pilot, prospective, monocentric study aimed at evaluating the rate of patients with circulating cancer cell/macrophage hybrid cells in the peripheral blood. The study will be conducted on a populatio...

Eligibility Criteria

Inclusion

  • Patient with breast cancer of any stage (stage I, II, III or IV) and any immunohistochemical subtype (triple-negative, HR+/HER2-negative or HER2-positive).
  • Patient not yet initiated on specific treatment for the stage of breast cancer at inclusion.
  • Available tumor sample (archived tumor block) : initial tumor or metastasis depending on the stage of the disease and availability.
  • Age ≥ 18 years old.
  • Patient affiliated to a Social Health Insurance in France.
  • Patient having signed informed consent prior to inclusion in the study and prior to any specific study procedure.

Exclusion

  • Associated pathology(ies) that may prevent the proper conduct of the procedure under consideration.
  • Pregnant or breastfeeding woman.
  • Any psychological, family, geographical or sociological condition that prevents compliance with the medical follow-up and/or procedures of the study protocol.
  • Patient who has forfeited his/her freedom by administrative or legal award or who is under legal protection (curatorship and guardianship protection of justice).
  • Patient who has presented another solid tumor (except breast or cervix carcinoma in situ) within 5 years.

Key Trial Info

Start Date :

March 31 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 29 2022

Estimated Enrollment :

61 Patients enrolled

Trial Details

Trial ID

NCT04818125

Start Date

March 31 2021

End Date

July 29 2022

Last Update

September 28 2022

Active Locations (1)

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Institut Universitaire du Cancer de Toulouse - Oncopole

Toulouse, France