Status:
COMPLETED
Prone Position Improves End-Expiratory Lung Volumes in COVID-19 Acute Respiratory Distress Syndrome
Lead Sponsor:
Istanbul University - Cerrahpasa
Conditions:
Acute Respiratory Distress Syndrome
Coronavirus
Eligibility:
All Genders
18+ years
Brief Summary
Covid-19 associated Acute Respiratory Distress Syndrome (ARDS) may present with profound hypoxemia not fully explained with pulmonary infiltrates. Accordingly, how prone positioning improves oxygenati...
Detailed Description
After initiation of invasive mechanical ventilation, initial ventilator settings were performed by the attending physician. These settings include titration of best PEEP to promote oxygenation if Spo2...
Eligibility Criteria
Inclusion
- Patients were considered eligible if they met the Berlin definition criteria for ARDS and intubated due to increased work of breathing and/or worsening hypoxemia. All patients had a positive Covid-19 real time Polymerase Chain Reaction test
Exclusion
- Exclusion criteria were; age \< 18 years, ARDS resulting from other risk factors, presence of chest drainage tubes, tracheostomy, pneumomediastinum, hemodynamic instability (systolic blood pressure \< 100 mmHg, lactate \> 2 mmol/l, or an increase in lactate concentrations for 20% in two consecutive blood gas analysis within 2 hours interval) and suspicion or confirmed pulmonary emboli.
Key Trial Info
Start Date :
September 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 1 2022
Estimated Enrollment :
43 Patients enrolled
Trial Details
Trial ID
NCT04818164
Start Date
September 1 2020
End Date
March 1 2022
Last Update
March 4 2022
Active Locations (1)
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1
Istanbul University-Cerrahpaşa
Istanbul, Turkey (Türkiye)