Status:
UNKNOWN
Application of Magnesium-rich Artificial Cerebrospinal Fluid in Subarachnoid Hemorrhage
Lead Sponsor:
First Affiliated Hospital Xi'an Jiaotong University
Conditions:
Intracranial Hemorrhage
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Intracerebral hemorrhage (ICH) is one of the common fatal types of cerebral apoplexy with high mortality and disability rates. Hematoma volume and complications of intracerebral hemorrhage are major p...
Detailed Description
This study is a prospective, interventional and double-blind randomized controlled clinical trial. After approval of the clinical registry, patients who meet the standards of inclusion and exclusion c...
Eligibility Criteria
Inclusion
- Patient is between 18 and 80 years of old;
- Patients with ICH rupture into the ventricle in the primary basal ganglia region or non-aneurysmal subarachnoid hemorrhage confirmed by skull imaging examination;
- Patient is admitted to hospital within 72 hours after onset;
- Informed consent of the patients or their family members, and signed informed consent for CSF replacement treatment.
Exclusion
- Non-spontaneous intracranial hemorrhage;
- Time from onset to admission is longer than 72 hours;
- The patient who needs surgical treatment;
- Contraindication of lumbar puncture, such as: cerebral hernia, severe intracranial hypertension, puncture site inflammation, blood system diseases, etc.;
- Patient has other serious diseases, such as heart failure, kidney failure, liver failure, etc;
- Patient or his/her relatives refuse to accept the above research plan.
Key Trial Info
Start Date :
April 30 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 1 2024
Estimated Enrollment :
72 Patients enrolled
Trial Details
Trial ID
NCT04819451
Start Date
April 30 2021
End Date
February 1 2024
Last Update
June 15 2022
Active Locations (1)
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1
First Affiliated Hospital of Xi'an Jiaotong University
Xi'an, Shaanxi, China, 710061