Status:
RECRUITING
Spinal Cord Lesion Detection in Multiple Sclerosis Using Novel MRI Sequences
Lead Sponsor:
University Hospital, Basel, Switzerland
Collaborating Sponsors:
Freie Akademische Gesellschaft Basel
Conditions:
Multiple Sclerosis (MS)
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study is to evaluate the sensitivity and intra-/inter-observer agreement of the averaged magnetization inversion recovery acquisitions (AMIRA) in spinal cord (SC) Multiple sclerosis (MS) lesion d...
Detailed Description
An averaged magnetization inversion recovery acquisitions (AMIRA) sequence was proposed for SC MRI. This MR-sequence delivers excellent contrast between the SC gray and white matter as well as between...
Eligibility Criteria
Inclusion
- Diagnosis of multiple sclerosis according to established international criteria
- Steroid free period: \> 4 weeks
- Participation in the Swiss MS Cohort (SMSC) study
Exclusion
- . History of severe (other) neurological, internal or psychiatric disease with SC affection
- MRI-related exclusion criteria (questionnaire):
- Paramagnetic and/or superparamagnetic foreign objects in the body (especially when located close to the SC)
- Pacemaker
- Claustrophobia
- Pregnancy, lactation
- Known hypersensitivity to gadolinium-based contrast media
Key Trial Info
Start Date :
July 18 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT04819737
Start Date
July 18 2022
End Date
December 1 2025
Last Update
March 12 2025
Active Locations (1)
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1
University Hospital Basel, Department of Neurology
Basel, Switzerland, 4031