Status:

UNKNOWN

Impact of Continuous Monitoring of PtC02 on Ventilatory Weaning in Neuro-injured Patients

Lead Sponsor:

Centre Hospitalier St Anne

Conditions:

Acute Brain Injury

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The investigators propose to study the value of non invasive continuous transcutaneous PtC02 monitoring for ventilatory withdrawal guidance in neuro-injured patients and to predict the risk of extubat...

Detailed Description

Extubation is part of the daily routine in intensive care and intensive care units. If the procedures for weaning from mechanical ventilation are well supervised by the establishment, in particular, o...

Eligibility Criteria

Inclusion

  • major patients (\>18 years)
  • admitted in ICU for an acute brain injury defined by a Glasgow Coma Scale \< 8 and the presence of a cerebral lesion identified on a referent Tomodensitometry (TDM) or Magnetic Resonance Imaging (MRI)
  • requiring mechanical ventilation during \>48 hours
  • eligible for a ventilatory weaning test

Exclusion

  • preexisting neurologic evolutive or degenerative affection or preexisting diaphragmatic dysfunction
  • preexisting decision of therapeutic limitation
  • impossibility to collect an informed consent
  • patients aged \<18 years
  • pregnancy
  • mental illness
  • impossibility for the subject to have a good comprehension of the study
  • lack of health insurance coverage

Key Trial Info

Start Date :

April 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2022

Estimated Enrollment :

98 Patients enrolled

Trial Details

Trial ID

NCT04819984

Start Date

April 1 2021

End Date

July 1 2022

Last Update

March 29 2021

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