Status:
COMPLETED
The Guiding Significance of Pupil Monitoring in the Perioperative Period
Lead Sponsor:
Yangzhou University
Conditions:
Pupil Diameter
Pupil Contraction Rate
Eligibility:
All Genders
65-95 years
Phase:
NA
Brief Summary
The pupil diameter is affected by both sympathetic and parasympathetic nerves, and its latency and response amplitude mainly reflect the functional status of the parasympathetic nerve. Clinically, the...
Eligibility Criteria
Inclusion
- Elderly patients undergoing general anesthesia for tracheal intubation, aged ≥65 years, operation time ≥2 hours, ASA classification I-III, and postoperative hospital stay for at least one week.
Exclusion
- It is known that this study involves persons who are allergic to general anesthetics;
- Patients with previous eye diseases;
- Head and neck surgery is not conducive to measurement;
- Patients with preoperative MMSE score less than 24 points or dementia due to various diseases;
- Patients planning to undergo neurosurgery;
- Those who use sedatives or antipsychotics before surgery;
- Patients with known central nervous system diseases, such as mental illness; Patients with hearing or vision impairment and unable to communicate normally.
Key Trial Info
Start Date :
November 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 30 2021
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT04820374
Start Date
November 1 2020
End Date
June 30 2021
Last Update
January 6 2023
Active Locations (1)
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1
the Affiliated Hospital of Yangzhou University
Yangzhou, Jiangsu, China