Status:

COMPLETED

Improving Wellbeing Through the Brain-Gut-Microbiota Axis

Lead Sponsor:

Pontificia Universidad Catolica de Chile

Collaborating Sponsors:

University of Chile

Instituto de Nutrición y Tecnología de los Alimentos

Conditions:

Healthy Lifestyle

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

Well-being is a state defined as the optimal psychological functioning and the experience associated with it, integrating physical and subjective factors. It has been suggested that the bidirectional ...

Detailed Description

Within the field of Psychology and Contemplative Sciences, the relationship and interdependence between the brain and body have been one of the most prevalent questions when it comes to understanding ...

Eligibility Criteria

Inclusion

  • Healthy adults of ≥ 18 to \& 65 years old of age.
  • Able to provide written consent.
  • Willing to provide stool samples and complete questionnaires, records, and diaries associated with the study
  • Willingness to discontinue consumption of probiotic supplements for the duration of the study.

Exclusion

  • Concurrent consumption of probiotics. Subjects will be eligible for participation, however, after a four (4) week wash-out period.
  • Known to be pregnant or breastfeeding or planning on becoming pregnant in the next two (2) months.
  • Positive pregnancy test in women of childbearing potential.
  • Use of antibiotic drugs (e.g., neomycin, rifaximin) within 1 month of the screening visit. The screened participant would be eligible to participate four (4) weeks after completing their course of antibiotics (wash-out period).
  • Subject with diabetes or metabolic diseases.
  • Subject with depression or psychiatric and neurological diseases.
  • Subject with IBS or gastrointestinal diseases.
  • Subject with immune disorders or with possible immune-deficient status (e.g. due to surgery).
  • Milk or soy allergy.

Key Trial Info

Start Date :

March 30 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 11 2022

Estimated Enrollment :

136 Patients enrolled

Trial Details

Trial ID

NCT04823533

Start Date

March 30 2021

End Date

March 11 2022

Last Update

June 24 2022

Active Locations (1)

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Pontificia Universidad Católica de Chile

Santiago, Santiago Metropolitan, Chile, 7790702