Status:

COMPLETED

Transarterial Chemoembolization Plus Hypofractionnated Radiotherapy vs. Surgery in Locally Advanced Hepatocellular Carcinoma: an IPTW Comparison

Lead Sponsor:

Hospices Civils de Lyon

Conditions:

Non-metastatic Hepatocellular Carcinoma

Eligibility:

All Genders

18+ years

Brief Summary

Patients with non-metastatic unresectable hepatocellular carcinoma

Eligibility Criteria

Inclusion

  • Age ≥18 years of age
  • ECOG 0-2
  • Histologically proven hepatocellular carcinoma or proven according to radiological and biochemical criteria (EASL-AASLD) in cirrhotic patients
  • Child-Pugh class A
  • Absence of truncular or lobar portal vein invasion, or suprahepatic vein invasion

Exclusion

  • Uncontrolled replication of hepatitis B virus
  • Transplanted liver
  • Previous abdominal irradiation
  • Previous treatment of HCC with systemic therapy, or with surgical resection in the 2 previous years
  • Metastatic illness

Key Trial Info

Start Date :

October 15 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 15 2021

Estimated Enrollment :

163 Patients enrolled

Trial Details

Trial ID

NCT04823715

Start Date

October 15 2020

End Date

January 15 2021

Last Update

April 1 2021

Active Locations (1)

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1

Croix-Rousse Hospital, Hospices Civils de Lyon

Lyon, France, 69004