Status:
COMPLETED
Analysis of the Efficacy of Cardiac Ischemic Postconditioning With New Clinical End-points Using Novel Biomarkers
Lead Sponsor:
Peter Ferdinandy
Collaborating Sponsors:
Semmelweis University Heart and Vascular Center
Szeged University
Conditions:
Acute Myocardial Infarction With ST Elevation
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The aim of the present study was to investigate the efficacy of ischemic postconditioning in acute myocardial infarction patients. The safety of patients enrolled in the study was ensured during the e...
Detailed Description
Over 18 years old men and women were enrolled in the study who arrived to 2 of the most acknowledged Hungarian cardiac centres due to acute myocardial infarction and fulfilled all inclusion and exclus...
Eligibility Criteria
Inclusion
- Subject must be \>18 years of age
- Myocardial infarction with elevated ST
- Chest pain onset less than 12 hours before PCI
- concordant ST elevation (\>0,1 mV) in at least 2 ECG leads
- Occluded main proximal or middle main coronary ('Thrombolysis In Myocardial Infarction' flow grade: 0) diagnosed with coronarography
- Coronary opened by PCI (TIMI 2 flow grade)
- Awake, conscious, co-operating patient, who is able to retain his breath for 10 sec
- Signed Patient Information Leaflet and Patient Informed Consent Form
Exclusion
- Cardiogenic shock
- Previous myocardial infarction in the area of the occluded coronary artery
- Occluded coronary with visible collateral branches
- Lack of co-operation
- Current left or right bundle branch block (LBBB)
- Malignant ventricle arrhythmia or atrial fibrillation
- Killip class \> 2
- Known renal failure
Key Trial Info
Start Date :
January 14 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 15 2018
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04824716
Start Date
January 14 2013
End Date
October 15 2018
Last Update
April 21 2021
Active Locations (3)
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1
Heart and Vascular Center, Semmelweis University
Budapest, Hungary, H-1122
2
Pharmahungary Group
Szeged, Hungary, 6722
3
Department of Invasive Cardiology of Cardiology Center, Faculty of Medicine, University of Szeged
Szeged, Hungary, H-6720