Status:
COMPLETED
Infectious Diseases in Aged Population
Lead Sponsor:
University Hospital, Grenoble
Conditions:
Respiratory Infections in Old Age
Bacteremia
Eligibility:
All Genders
65+ years
Phase:
NA
Brief Summary
The increasing number of persons \>65 years of age form a special population at risk for nosocomial and other health care-associated infections. The vulnerability of this age group is related to impai...
Detailed Description
An emerging public health challenge is to protect the growing ageing population from infectious diseases, which can significantly impact the quality of life of those affected. The vulnerability of th...
Eligibility Criteria
Inclusion
- Inclusion Criteria For Case:
- Hospitalized adults 65 years or older,
- Presenting with bacteremia with positive blood culture (excluding catheter related infections) and/or
- WHO Severe Acute Respiratory Infection (SARI) case definition
- Upper respiratory infection = SARI (fever or history of fever \>38°C, cough, onset of the disease within the last 10 days and requires hospitalisation)
- Lower respiratory infection = SARI with confirmed CT/CHR
- Informed consent form signed
- Patient affiliated to social security insurance
- Exclusion Criteria For Case:
- Bedridden or terminally ill patient (based upon a threshold of ADL: ≤2 TBD, or CLINICAL FRAILTY SCALE: ≥8 )
- Patients that refuse the 3- and 6-months follow-up phone call assessments
- Patients that will not be able to answer the 3- and 6-months follow-up phone call assessments via a nurse
- Subject in exclusion period for another study,
- Subject who cannot be contacted in an emergency
- Persons referred to in Articles L1121-5 to L1121-8 of the French code of public health (this corresponds to all persons protected: pregnant or parturient women, breastfeeding mothers, persons deprived of liberty by judicial or administrative decision, persons subject to a legal protection measure).
- Inclusion Criteria For Controls
- Same age (+/- 3 years)
- same sex,
- without suspicion of infection
- Hospitalized during the past or upcoming month in the same centre.
- Informed consent form signed
- Patient affiliated to social security insurance
- Exclusion Criteria For Controls
- Bedridden or terminally ill patient (based upon a threshold of ADL: ≤2 TBD, or CLINICAL FRAILTY SCALE: ≥8 )
- Patients that refuse the 3- and 6-months follow-up phone call assessments
- Patients that will not be able to answer the 3- and 6-months follow-up phone call assessments via a nurse
- Subject in exclusion period for another study,
- Subject who cannot be contacted in an emergency
- Persons referred to in Articles L1121-5 to L1121-8 of the French code of public health (this corresponds to all persons protected: pregnant or parturient women, breastfeeding mothers, persons deprived of liberty by judicial or administrative decision, persons subject to a legal protection measure)
Exclusion
Key Trial Info
Start Date :
April 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 30 2023
Estimated Enrollment :
521 Patients enrolled
Trial Details
Trial ID
NCT04825132
Start Date
April 1 2021
End Date
November 30 2023
Last Update
August 13 2025
Active Locations (22)
Enter a location and click search to find clinical trials sorted by distance.
1
University Hospital Amiens
Amiens, France
2
Hospital Chambery
Chambéry, France
3
Groupe Hospitalier Sud Ile de France
Melun, France
4
Groupement Hospitalier portes de Provence
Montélimar, France