Status:
RECRUITING
Cognition and Motor Learning Post-stroke
Lead Sponsor:
University of Southern California
Conditions:
Stroke
CVA (Cerebrovascular Accident)
Eligibility:
All Genders
45-85 years
Phase:
EARLY_PHASE1
Brief Summary
This project seeks to determine how post-stroke cognitive impairment moderates motor learning during walking in older adults with chronic stroke and identify brain structural markers that mediate this...
Eligibility Criteria
Inclusion
- Unilateral stroke
- Stroke occurred more than 6 months prior
- Paresis confined to one side
- Independently ambulatory (including the use of assistive devices)
- Able to walk for 5 minutes without stopping
- Answers no to all general health questions on the PAR-Q+
- Willingness to complete study procedures
Exclusion
- Brainstem or cerebellar stroke
- Aphasia (expressive, receptive, or global)
- Any major musculoskeletal or non-stroke neurological condition that interferes with the assessment of sensorimotor or cognitive function
- Metal in the head (except in the mouth), implanted cranial or thoracic devices that violate MRI safety regulations
- Uncontrolled hypertension (\>160/110mmHg)
- Concurrent physical therapy
- Claustrophobia
- Significant cognitive deficit or dementia (\<20 on MoCA)
- Inability to give informed consent
Key Trial Info
Start Date :
January 16 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 14 2026
Estimated Enrollment :
65 Patients enrolled
Trial Details
Trial ID
NCT04829071
Start Date
January 16 2023
End Date
December 14 2026
Last Update
November 4 2025
Active Locations (1)
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1
Center for Health Professions
Los Angeles, California, United States, 90033