Status:

COMPLETED

Correlation Between Myocardial Deformation and Coronary Artery Tortuosity in Patients With Hypertrophic Cardiomyopathy

Lead Sponsor:

Henan Provincial People's Hospital

Conditions:

Myocardial Deformation

Coronary Artery Anomaly

Eligibility:

All Genders

18-85 years

Brief Summary

Correlation between Myocardial Deformation and Coronary Tortuosity and Analysis of Genetic Factors Among Hypertrophic Cardiomyopathy Patients

Detailed Description

Excessive tortuosity of the coronary arteries (TCA) is a somewhat common finding in patients referred for coronary angiography, reported in 14-40% of patients referred for angiography. The presence of...

Eligibility Criteria

Inclusion

  • Subjects must meet all the following inclusion criteria to be eligible for participation in this study
  • 18\<age≤85;
  • Patients with hypertrophic cardiomyopathy and without hypertrophic cardiomyopathy undergoing coronary angiography and echocardiography;
  • Willing to sign informed consent.

Exclusion

  • Subjects who meet any of the following exclusion criteria are not to be enrolled in this study
  • All coronary arteries can not be shown clearly in coronary angiography
  • Prior coronary artery bypass surgery, valve prosthesis
  • Connective tissue disease
  • Cardiac dilatation(left ventricular end diastolic diameter, ≥55mm male,≥50mm female )
  • Congenital heart failure, LVEF\<35%
  • Coronary total occlusion, changes in coronary morphology, such as long stents implantation(≥12mm)

Key Trial Info

Start Date :

December 1 2017

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 1 2022

Estimated Enrollment :

302 Patients enrolled

Trial Details

Trial ID

NCT04830787

Start Date

December 1 2017

End Date

August 1 2022

Last Update

August 19 2022

Active Locations (1)

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Central China Fuwai Hospital, Heart Center of Henan Provincal People's Hospital

Zhengzhou, Henan, China, 450000