Status:
RECRUITING
Periodontitis and Inflammation
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Conditions:
Periodontitis
Peri-Implantitis
Eligibility:
All Genders
18+ years
Brief Summary
Today, to understand pathogenic mechanisms involved in periodontitis and peri-implantitis remains a challenge to identify biomarkers or therapeutic targets to improve prevention and screening, as well...
Detailed Description
Today, to understand pathogenic mechanisms involved in periodontitis and peri-implantitis remains a challenge to identify biomarkers or therapeutic targets to improve prevention and screening, as well...
Eligibility Criteria
Inclusion
- Common criteria for all patient groups
- Patient \> 18 years old
- Patient affiliated to a social security system, beneficiary or beneficiary of a right other than AME
- Patient who speaks and understands French well enough to be able to read and understand the study information note.
- Patient who does not object to his participation in the study
- Specific criteria:
- \- Case Periodontitis: Patient with localized or generalized periodontitis, stage 3 or 4. The diagnosis of periodontitis is based on the elements found during the interview and clinical examination
- \- Case peri-implantitis: Patients with at least 1 implant affected by peri-implantitis. Diagnosis is based on the findings of the interview, clinical examination and radiographic examination.
- Control group:
- Patient with gingival health on intact or reduced periodontium with no history of periodontitis or peri-implantitis and requiring surgical care such as dental avulsion and pre-prosthetic periodontal corrective/aesthetic surgeries (coronal elongation, neck alignment.)
Exclusion
- Patients who have received antibiotic prophylaxis, antibiotic therapy, or anti-inflammatory treatment within 3 months prior to inclusion
- Pregnant or breastfeeding women
- Patient included in another interventional research protocol or in a period of exclusion.
- Patients under guardianship, curatorship or legal protection.
- Patient having expressed his opposition to participate in the research
Key Trial Info
Start Date :
February 15 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
November 15 2028
Estimated Enrollment :
144 Patients enrolled
Trial Details
Trial ID
NCT04831060
Start Date
February 15 2023
End Date
November 15 2028
Last Update
May 2 2025
Active Locations (2)
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1
Service d'odontologie, hôpital Charles Foix
Ivry-sur-Seine, France, 94200
2
Dentistry department- Rothschild hospital
Paris, France, 75012