Status:

TERMINATED

Real World Pharmacokinetics of Immune Checkpoint Inhibitors

Lead Sponsor:

Radboud University Medical Center

Conditions:

Cancer

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Rationale: Real-world pharmacokinetic data from cancer patients treated with immune checkpoint inhibitors (ICIs) are sparse. Moreover, pharmacokinetic parameters may be associated with response to ICI...

Eligibility Criteria

Inclusion

  • Treatment with immune checkpoint inhibitors (atezolizumab (Tecentriq®), avelumab (Bavencio®), cemiplimab (Libtayo®), durvalumab (Imfinzi®), ipilimumab (Yervoy®), nivolumab (Opdivo®) and pembrolizumab (Keytruda®))
  • Willingness and ability to provide written informed consent
  • Age 18 years or older

Exclusion

  • n/a (real-world)

Key Trial Info

Start Date :

September 15 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 15 2023

Estimated Enrollment :

19 Patients enrolled

Trial Details

Trial ID

NCT04833075

Start Date

September 15 2021

End Date

May 15 2023

Last Update

May 31 2023

Active Locations (1)

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1

Radboudumc

Nijmegen, Gelderland, Netherlands, 6525 GA