Status:

COMPLETED

Effectiveness and Safety of Pharmacopunture Therapy for Chronic Low Back Pain: A Pragmatic Randomized Controlled Trial

Lead Sponsor:

Jaseng Medical Foundation

Collaborating Sponsors:

Korea Institute of Oriental Medicine

Conditions:

Chronic Low-back Pain

Eligibility:

All Genders

19-70 years

Phase:

NA

Brief Summary

This is a multi-center, 2-arm parallel pragmatic randomized controlled trial that will compare pharmacopuncture therapy with physical therapy for chronic low back pain.

Detailed Description

This is a multi-center, 2-arm parallel pragmatic randomized controlled trial that will compare pharmacopuncture therapy with physical therapy for chronic low back pain. Participants who voluntarily si...

Eligibility Criteria

Inclusion

  • low back pain for more than 6 months
  • Numeric rating scale (NRS) score for low back pain 5 or more
  • 19-70 years old
  • participants who agreed and signed informed consent form

Exclusion

  • Spine metastasis of cancer, acute fracture of spine, or spine dislocation
  • Progressive neurologic deficits or severe neurologic deficits
  • Soft tissue diseases that can induce low back pain (ie. cancer, fibromyalgia, rheumatoid arthritis, gout, etc)
  • Presence of chronic underlying disease which can interfere the efficacy or interpretation (ie. stroke, myocardial infarct, kidney disease, dementia, diabetic neuropathy, epilepsy, etc)
  • Concurrent use of steroids, immunosuppressants, or psychotropic medications
  • Hemorrhagic disease, severe diabetes or taking anticoagulant drug
  • Participants who took NSAIDs or pharmacopuncture within 1 week
  • Pregnant or lactating women
  • Participants who had undergone lumbar surgery within 3 months
  • Participants who had participated in other clinical trial within 1 month, or have plan for participation in other trial during follow up period of this trial
  • Participants who can not write informed consent
  • Participants who is difficult to participate in the trial according to investigator's decision

Key Trial Info

Start Date :

June 10 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 26 2022

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04833309

Start Date

June 10 2021

End Date

February 26 2022

Last Update

December 18 2024

Active Locations (4)

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Page 1 of 1 (4 locations)

1

Jaseng Hospital of Korean Medicine

Seoul, Gangnam-Gu, South Korea, 135-896

2

Bucheon Jaseng Hospital of Korean Medicine

Bucheon-si, Gyeonggi Province, South Korea, 14598

3

Haeundae Jaseng Hospital of Korean Medicine

Busan, South Korea, 48102

4

Daejeon Jaseng Hospital of Korean Medicine

Daejeon, South Korea, 35262