Status:

UNKNOWN

Verticalization Robotic Exoskeleton DoC

Lead Sponsor:

Memorial Hermann Health System

Conditions:

Brain Injuries

Disorder of Consciousness

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

Mobilization, specifically verticalization, has been shown to play a role in enhancing consciousness. Vestibular stimulation has the potential to influence the neural substrate of consciousness, but t...

Eligibility Criteria

Inclusion

  • unresponsive wakefulness syndrome/vegetative state (UWS/VS) or minimally conscious state (MCS) following traumatic brain injury (TBI), intracerebral bleeding, ischemic infarction, or hypoxic brain injury
  • Medical clearance by a physician
  • 18-75 years old
  • Mobilization into standing for at least 10 minutes without signs of orthostasis

Exclusion

  • Time since injury less than 4 weeks or more than 6 months
  • Mobilization into standing lasts more than 30 minutes
  • Severe osteoporosis
  • Muscle tone that prevents joint motion (Modified Ashworth Scale (MAS) 4)
  • Unstable fractures
  • Decubiti on areas contacted by robotic mobility device (i.e. heels, tibia, greater trochanter, ischial tuberosity, sacrum)
  • Inability to fit device requirements\*
  • Height 4'8"-6'4", Weight 88-222 lbs., Hip Flexion 0-90˚, Knee Flexion 0-90˚, Plantigrade

Key Trial Info

Start Date :

April 21 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2021

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT04833543

Start Date

April 21 2021

End Date

December 1 2021

Last Update

September 1 2021

Active Locations (1)

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1

TIRR Memorial Hermann

Houston, Texas, United States, 77030