Status:
SUSPENDED
Radiotherapy Combined With Immunotherapy for Brain Metastases of Non-small Cell Lung Cancer
Lead Sponsor:
Tongji Hospital
Collaborating Sponsors:
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan University
Conditions:
Non Small Cell Lung Cancer
Eligibility:
All Genders
18-75 years
Brief Summary
This is a Retrospective, Multicenter, Controlled Study to Evaluate Immunotherapy and Radiotherpay for Brain Lesions as a Potential Treatment for Patients with Brain Metastasis in non-small cell lung c...
Eligibility Criteria
Inclusion
- Experimental group:
- 18 years old ≤ age ≤ 75 years old, no gender limitation;
- NSCLC who have received radiotherapy for brain lesions + PD-1/PD-L1 immunotherapy;
- Histologically confirmed as NSCLC;
- Imaging confirmed brain metastasis (CT or MRI);
- The presence of imaging-evaluable lesions can be evaluated in accordance with RECIST 1.1
- Control group:
- 1 18 years old ≤ age ≤ 75 years old, no gender limitation; 2 NSCLC who has received radiotherapy for brain lesions; 3 Histologically confirmed as non-small cell lung cancer; 4 Imaging confirmed brain metastasis (CT or MRI); 5 The presence of imaging-evaluable lesions can be evaluated in accordance with RECIST 1.1
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Exclusion
- 1 The age is less than 18 years old, regardless of gender; 2 Histologically confirmed as NSCLC 3 Imaging confirmed the absence of brain metastases 4 NSCLC with brain metastasis only received chemotherapy or targeted therapy, and did not receive radiotherapy or immunotherapy
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Key Trial Info
Start Date :
January 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 31 2021
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT04835025
Start Date
January 1 2018
End Date
July 31 2021
Last Update
April 8 2021
Active Locations (1)
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1
Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430030, Hubei, P. R. China
Wuhan, Hubei, China, 430030