Status:
COMPLETED
Management of Hypertension in the Early Postpartum: a Randomized Controlled Trial
Lead Sponsor:
Federal University of Paraíba
Conditions:
Pregnancy-Induced Hypertension in Postpartum
Postpartum Pre-Eclampsia
Eligibility:
FEMALE
18-50 years
Phase:
PHASE4
Brief Summary
In hypertensive mothers, it is common in clinical practice to substitute methyldopa for another medication, such as captopril, immediately after delivery, which may, as a consequence, cause a rebound ...
Detailed Description
Objective: To evaluate blood pressure control during the immediate postpartum in hypertensive women who had used methyldopa during pregnancy, comparing continuation of that drug with switching it for ...
Eligibility Criteria
Inclusion
- puerpera;
- hypertensive;
- use of methyldopa during pregnancy at a minimum dose of 750 mg / day, for at least 07 days before delivery
Exclusion
- Use of other antihypertensive medications or illicit drugs that may interfere with maternal hemodynamics, and / or Contraindications to the use of captopril or methyldopa
Key Trial Info
Start Date :
May 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2022
Estimated Enrollment :
180 Patients enrolled
Trial Details
Trial ID
NCT04835233
Start Date
May 1 2021
End Date
December 31 2022
Last Update
December 28 2023
Active Locations (1)
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1
UFPB Paraíba Federal University
João Pessoa, Paraíba, Brazil, 58050-585