Status:
UNKNOWN
MRI T2* Mapping of Myocardium, Liver, Pancreas and Pituitary Gland
Lead Sponsor:
Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Conditions:
Iron Overload
Eligibility:
All Genders
6-25 years
Phase:
NA
Brief Summary
All patients were investigated using a 3T MRI and 1,5 T MRI scanners. For myocardium, pancreas and pituitary gland iron overload quantification in children we have used special sequences for T2\*-mapp...
Detailed Description
All patients were investigated using a 3T MRI scanner (Philips Achieva) and 1,5 T MRI scanner (GE Signa) with 8-channel surface coil for body scanning. For myocardium, pancreas and pituitary gland iro...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Age under 25 y.o.;
- A history of transfusion-dependent anemia of various origins.
- indications for the appointment of chelation therapy
- Non-inclusion criteria:
- Age over 25 y.o.
- The number of RBC transfusions previously received by the patient is less than 10
- Exclusion criteria:
- Absolute contraindications to magnetic resonance imaging (pacemaker, ferromagnetic implants, etc.);
- Refusal to sign the informed consent.
Exclusion
Key Trial Info
Start Date :
January 21 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 21 2023
Estimated Enrollment :
152 Patients enrolled
Trial Details
Trial ID
NCT04835285
Start Date
January 21 2020
End Date
January 21 2023
Last Update
April 8 2021
Active Locations (1)
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1
Dmitry Rogachev National Medical Research Center Of Pediatric Hematology, Oncology and Immunology
Moscow, Samory-Mashela,1, Russia, 11198