Status:

UNKNOWN

Biometric and Biological Data for Diagnosis and Therapy of Pain Patients

Lead Sponsor:

RWTH Aachen University

Collaborating Sponsors:

Grünenthal GmbH

Conditions:

Small Fiber Neuropathy

Eligibility:

All Genders

18+ years

Brief Summary

In order to meet the challenge of an unambiguous diagnosis and effective therapy of SFN or the prognosis of susceptibility to the development of SFN, this project aims to create a data basis on which ...

Detailed Description

Bio2Watch: In this clinical project part biometric patient data of 24 SFN patients, 3 cancer patients and 21 subjects (control group) will be collected for a period of one year using a PainWatch. The ...

Eligibility Criteria

Inclusion

  • Group A: Criteria 1-5 Group B: Criteria 2-5 Group C: Criteria 2-6 Group D: Criteria 2-4
  • Small fiber neuropathy (after clinical examination or QST or skin biopsy findings)
  • Legal age
  • Written declaration of consent
  • Persons who are legally competent and mentally capable of following the instructions of the staff
  • Sufficient affinity for independent handling of the technology used (PainWatch incl. the corresponding apps) for daily digital pain recording
  • Imminent initiation of neurotoxic chemotherapy in cancer with solid tumors (preferably of the gastrointestinal tract) There are no plans for follow-up recruitment in case no neuropathy develops after chemo.

Exclusion

  • For all Groups:
  • Persons who are accommodated in an institution by order of the authorities or courts
  • Persons who are in a dependent or employment relationship with the auditor
  • For test persons: Exclusion, if they carry a known pain-relevant genetic variant/mutation or suffer from a chronic pain disorder analogous to migraine or chronic back pain.

Key Trial Info

Start Date :

October 10 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

October 1 2023

Estimated Enrollment :

68 Patients enrolled

Trial Details

Trial ID

NCT04835779

Start Date

October 10 2020

End Date

October 1 2023

Last Update

January 9 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Uniklinik RWTH Aachen, Klinik für Palliativmedizin

Aachen, North Rhine-Westphalia, Germany, 52074