Status:
SUSPENDED
Neurosensory Abnormalities in SymptomAtic Ocular Surface Patients (NASA)
Lead Sponsor:
Tufts Medical Center
Collaborating Sponsors:
CooperVision International Limited (CVIL)
Bausch & Lomb Incorporated
Conditions:
Dry Eye
Neuropathic Pain
Eligibility:
All Genders
18+ years
Brief Summary
This study is designed to measure how common nerve abnormalities are within a group of patients who feel discomfort within their eyes.
Eligibility Criteria
Inclusion
- Presents with ocular surface discomfort or for dry eye care
- Best corrected visual acuity of 20/40 or better in each eye
- Subject reported duration of symptoms of at least 3 months
- 100 subjects will be required to be habitual contact lens wearers as defined by use of contact lenses at least 5 hours per day at least 5 days per week for the last year.
Exclusion
- Use of contact lenses on the day of the visit
- Pregnant or nursing
- Irregular corneas (e.g., ectatic disease, transplantation, or corneal dystrophies)
- Ocular surgery in the past 3 months
- Ocular infection in the past 3 months
- Active ocular allergies
Key Trial Info
Start Date :
July 2 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
1000 Patients enrolled
Trial Details
Trial ID
NCT04838223
Start Date
July 2 2021
End Date
December 1 2025
Last Update
September 22 2025
Active Locations (16)
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1
Canyon City Eye Care
Azusa, California, United States, 91702
2
Western University of Health Sciences
Pomona, California, United States, 91766
3
University of California at San Francisco - Francis I Proctor Foundation
San Francisco, California, United States, 94143
4
Bruce W. Carter VA Medical Center
Miami, Florida, United States, 33125