Status:
RECRUITING
Sympathetic Transduction in Obesity-associated Hypertension (OB-HTN)
Lead Sponsor:
University of Texas Southwestern Medical Center
Conditions:
Hypertension
Obesity
Eligibility:
All Genders
18-55 years
Phase:
EARLY_PHASE1
Brief Summary
The purpose of this study is to understand how the nervous system communicates to blood vessels to increase blood pressure during stress. The study will also investigate how hypertension and obesity i...
Eligibility Criteria
Inclusion
- Control - BMI\<30, age 18-55
- Hypertensive - BMI\<30, age 18-55, diagnosis of hypertension by 24-hour ambulatory blood pressure monitoring Obese- BMI\>30, age 18-55 Obese-hypertensive- BMI\>30, age 18-55, diagnosis of hypertension by 24-hour ambulatory blood pressure monitoring
Exclusion
- All groups - presence of other significant cardiovascular disease, renal disease, history of smoking, diabetes,
Key Trial Info
Start Date :
July 18 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 31 2026
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04838678
Start Date
July 18 2021
End Date
August 31 2026
Last Update
August 24 2025
Active Locations (1)
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1
University of Texas Southwestern Medical Center
Dallas, Texas, United States, 75231