Status:

UNKNOWN

Comparing Sevoflurane With Propofol Sedation in ESRF Patients

Lead Sponsor:

University of Malaya

Conditions:

Sevoflurane

Kidney Diseases

Eligibility:

All Genders

18-80 years

Phase:

PHASE4

Brief Summary

End-stage renal failure (ESRF) cohorts undergo brachiocephalic fistula(BCF) transposition with supraclavicular block. However, this is inadequate because the incision may extend to the axillary region...

Detailed Description

Regional anesthesia has been shown to be superior to general anesthesia in end-stage renal disease (ESRF) patients undergoing brachiocephalic transposition by ensuring graft patency, reducing pharmaco...

Eligibility Criteria

Inclusion

  • Patient with end stage renal failure, dialysis dependent undergoing transposition of brachiocephalic fistula repair
  • American Society of Anesthesiology Physical Status Classification System (ASA) II or III

Exclusion

  • Patient refusal
  • History or family history of malignant hyperthermia
  • Known allergy to propofol or local anaesthetic agent
  • Patients who have taken neuroleptics, benzodiazepine over 2 weeks within 1 month
  • Chronic use of alcohols/ opioid
  • Active lungs disease (eg. acute exacerbation of chronic obstructive pulmonary disease)
  • Active and significant cardiac disease (eg. decompensated congestive cardiac failure, recent myocardial infarction)
  • End-stage heart failure with left ventricular ejection fraction \< 30%
  • Recent (\< 3 months) cerebrovascular accident

Key Trial Info

Start Date :

April 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 30 2022

Estimated Enrollment :

36 Patients enrolled

Trial Details

Trial ID

NCT04839536

Start Date

April 1 2021

End Date

April 30 2022

Last Update

April 9 2021

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