Status:

COMPLETED

Anemia in Patients With Endocarditis

Lead Sponsor:

Rigshospitalet, Denmark

Conditions:

Anemia

Endocarditis, Bacterial

Eligibility:

All Genders

18+ years

Brief Summary

Prospective study of prevalence and deep charecterization of anemia in patients with endocarditis from diagnosis undtill 6 months after discharge.

Detailed Description

Anemia is an adverse prognostic marker in both cardiac diseases and infectious diseases. In patients with bacterial endocarditis (IE), anemia has a prevalence of 55-80%. In a sub-study to our POET I t...

Eligibility Criteria

Inclusion

  • IE-patients:
  • • Infectious endocarditis, defined by Duke criteria

Exclusion

  • • Known rheumatic disease or immune defect
  • TAVI/TEVAR patients:
  • Inclusion Criteria:
  • • Scheduled for a TAVI/TEVAR procedure
  • Exclusion criteria:
  • Clinical suspicion of infection
  • Known rheumatic disease or immune defect
  • Bacterial patients without IE (short infection):
  • Inclusion criteria
  • Patients admitted with an infection with gram positive bacteria, without IE Exclusion criteria
  • Known rheumatic disease or immune defect
  • Blood donors:
  • Exclusion criteria:
  • Antibiotic treatment within the last 2 months
  • Cancer, rheumatic disease or other known inflammatory disease
  • Surgery within the last 3 months
  • Pregnancy

Key Trial Info

Start Date :

March 22 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 29 2023

Estimated Enrollment :

209 Patients enrolled

Trial Details

Trial ID

NCT04840225

Start Date

March 22 2021

End Date

June 29 2023

Last Update

September 26 2025

Active Locations (1)

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1

Rigshospitalet

Copenhagen, Denmark, 2100