Status:

COMPLETED

The Effect of Vitamin D Supplementation in Overweight and Obese Pregnant Women

Lead Sponsor:

KK Women's and Children's Hospital

Conditions:

Overweight and Obesity

Eligibility:

FEMALE

21-45 years

Phase:

NA

Brief Summary

To understand the role of vitamin D supplementation on pregnancy outcomes and metabolic status in overweight and obese pregnant women.

Detailed Description

The effects of vitamin D supplementation on pregnancy outcomes and metabolic status of overweight and obese pregnant women remain uncertain. In particular, the dosage of vitamin D supplementation has ...

Eligibility Criteria

Inclusion

  • Gestation ≤16weeks (16 weeks + 6 days) upon intervention
  • Pre-pregnancy BMI ≥25 kg/m2
  • Aged 21-45 years
  • Willing and able to provide written, informed consent

Exclusion

  • Having current or past hypo/hyperparathyroidism, hypercalciuria, hypercalcemia or osteomalacia
  • History of renal disease (including kidney stones and etc.), liver dysfunction, tuberculosis or sarcoidosis
  • Pre-existing diabetes mellitus or chronic hypertension
  • Taking lipid-lowering medicine
  • Gestational diabetes (as confirmed by oral glucose tolerance test) or gestational hypertensive disorder
  • Multiple pregnancy

Key Trial Info

Start Date :

May 28 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 31 2024

Estimated Enrollment :

274 Patients enrolled

Trial Details

Trial ID

NCT04841265

Start Date

May 28 2021

End Date

March 31 2024

Last Update

July 8 2024

Active Locations (1)

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KK Women's and Children's Hospital

Singapore, Singapore