Status:

TERMINATED

HFNC Vs LFNC in Patients with AF Undergoing RFCA Under Deep Sedation.

Lead Sponsor:

Maastricht University Medical Center

Conditions:

Deep Sedation

Oxygen Therapy

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Oxygen supplementation through high flow nasal cannula (HFNC) may reduce the incidence of desaturation and hypoxemia during deep sedation at radiofrequency catheter ablation (RFCA procedures).This stu...

Detailed Description

Desaturation may occur in patients under deep sedation which results in an elevated risk for perioperative adverse events including hypoxemia (1-3). The incidence of hypoxemia was 168 per 1000 in a ge...

Eligibility Criteria

Inclusion

  • Adults undergoing an elective RFCA for atrial fibrillation in the Maastricht UMC Cardiac Catheter Labs under deep sedation administered by a clinician anesthesiology

Exclusion

  • Age under 18 years
  • Body Mass Index (BMI) \> 32 kg/m²
  • Diagnosed Sleep Apnoea Syndrome (SAS)
  • Chronic Pulmonary Obstructive Disease (COPD) gold IV and COPD gold III with frequent or recent exacerbation
  • Diagnosed pulmonary or cardiac condition requiring chronic oxygen therapy
  • Complete nasal obstruction
  • Active nose bleeding
  • Untreated pneumothorax (pre- existing)
  • Recent upper airway surgery
  • Recent base of skull fracture
  • Expected difficult airway

Key Trial Info

Start Date :

January 4 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 18 2024

Estimated Enrollment :

141 Patients enrolled

Trial Details

Trial ID

NCT04842253

Start Date

January 4 2022

End Date

November 18 2024

Last Update

February 20 2025

Active Locations (1)

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1

Maastricht UMC

Maastricht, Netherlands, 6229HX