Status:
RECRUITING
Evaluation of Cortisol and Bile Acids Metabolism in Obese Patients
Lead Sponsor:
University Hospital, Lille
Conditions:
Obesity
Eligibility:
FEMALE
18+ years
Brief Summary
Bariatric surgery is currently the most efficient treatment for obesity. The sustained weight loss and metabolic improvement seen following Roux-en-Y gastric bypass (RYGB), is explained partly by modi...
Eligibility Criteria
Inclusion
- Non-menopausal women
- BMI between 35 and 50 kg/m² included
- Social insured
- Ability to give consent
Exclusion
- moderate and severe kidney insufficiency
- hepatic insufficiency
- known gallbladder lithiasis
- history of cholecystectomy or cholecystectomy planned during the gastric bypass
- history of bariatric surgery except gastric band and gastric balloon
- history of type 1
- treatment interfering with the cortisol metabolism: taking oral or inhaled glucocorticoids within the last 6 months
- treatment by BA as ursodeoxycholic acid, bile acids sequester, statin, fibrate stopped less than 4 weeks ago
Key Trial Info
Start Date :
March 30 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 30 2026
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT04844684
Start Date
March 30 2023
End Date
December 30 2026
Last Update
December 23 2025
Active Locations (1)
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1
Hôpital Huriez - Service d'endocrinologie, diabétologie, nutrition et métabolisme
Lille, France