Status:
COMPLETED
Effect of Mediterranean Diet in Obese Adolescents With Nonalcoholic Fatty Liver Disease
Lead Sponsor:
Gazi University
Collaborating Sponsors:
Izmir Katip Celebi University
Conditions:
Nonalcoholic Fatty Liver Disease
Eligibility:
All Genders
11-18 years
Phase:
NA
Brief Summary
The aim of this study was to evaluate the effects of mediterranean and low-fat diet on hepatic fat, inflammation markers and oxidative stress in adolescents with nonalcoholic fatty liver disease. This...
Detailed Description
This study was conducted to evaluate the effect of Mediterranean and low-fat diet on hepatic fat, inflammation and oxidative stress in obese adolescents with nonalcoholic fatty liver disease (NAFLD). ...
Eligibility Criteria
Inclusion
- Being between the ages of 11-18
- Being obese (BMI ≥95.persentil)
- Getting a diagnosis of Grade≥1 NAFLD
Exclusion
- Existence of liver disease (wilson,hepatitis etc.) other than NAFLD
- Drinking alcohol
- Having a history of type 1 and type 2 diabetes
- Using drugs that can cause steatosis
- Using lipid-lowering drugs
- Using weight loss medications
- Having applied dietary therapy for any disease and weight loss
- Existence of a chronic inflammatory disease
- Existence of cancer
- Thyroid dysfunction (hyperthyroid and hypothyroidism)
- Existence of a history of hepatic virus infection
- Having a history of parenteral nutrition
- Being pregnant and breastfeeding
- Receiving antibiotic treatment within 3 months prior to the study
- Regularly consuming foods containing probiotic and prebiotic properties and / or using nutritional supplements
Key Trial Info
Start Date :
January 5 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 29 2020
Estimated Enrollment :
44 Patients enrolled
Trial Details
Trial ID
NCT04845373
Start Date
January 5 2020
End Date
November 29 2020
Last Update
April 15 2021
Active Locations (1)
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1
İzmir Tepecik Training and Research Hospital
Izmir, Turkey (Türkiye)