Status:

COMPLETED

REVEAL-CKD: Prevalence and Consequences of Undiagnosed Chronic Kidney Disease

Lead Sponsor:

AstraZeneca

Conditions:

Chronic Kidney Disease

Eligibility:

All Genders

18+ years

Brief Summary

This is a retrospective, multinational, non-interventional, observational study. A series of cohort studies will be conducted to assess the prevalence of undiagnosed stage 3 CKD in each region. The st...

Detailed Description

This study is a retrospective, multinational, non-interventional observational study. The study does not attempt to test any specific a priori hypothesis; it is descriptive only and will collect data ...

Eligibility Criteria

Inclusion

  • At least two consecutive eGFR laboratory tests with values ≥30 and \<60 mL/min/1.73 m2 (Stage 3A or 3B) that are \>90 and ≤730 days apart. The index date is the date of the second eGFR measure meeting the criteria for stage 3 CKD
  • At least 12 months of continuous presence in the database or registration in the data prior to the first qualifying eGFR (for data sources with information on enrolment)
  • Age ≥18 years at index date

Exclusion

  • Solid organ transplant before the study index date
  • Any evidence of advanced CKD (stage 4, 5) based on CKD diagnostic codes, or renal replacement therapy before the index date

Key Trial Info

Start Date :

December 15 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

November 13 2023

Estimated Enrollment :

1006361 Patients enrolled

Trial Details

Trial ID

NCT04847531

Start Date

December 15 2020

End Date

November 13 2023

Last Update

December 16 2024

Active Locations (13)

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Page 1 of 4 (13 locations)

1

Research Site

Louisville, Kentucky, United States, 40202

2

Research Site

Cambridge, Massachusetts, United States, 02140

3

Research Site

Ann Arbor, Michigan, United States, 48108

4

Research Site

Sydney, New South Wales, Australia, 2040