Status:
UNKNOWN
The Effect of Probiotic Lactobacillus Reuteri Prodentis Consumption on Gingival Crevicular Fluid Inflammatory Response and Metagenomic Profiles of Oral Microbiome in Orthodontic Patients.
Lead Sponsor:
Trisakti University
Collaborating Sponsors:
Duke-NUS Graduate Medical School
Indonesia University
Conditions:
Healthy Subjects With Fixed Orthodontics
Eligibility:
All Genders
18-28 years
Phase:
NA
Brief Summary
In this study, researchers will test the effectiveness of probiotic consumption against oral pathogenic bacteria and reduce the occurrence of gingival inflammation in subjects using orthodontic fixed ...
Detailed Description
Rationale and background of the study Aesthetics is a primary consideration for patients seeking orthodontic treatment. However, apart from esthetic aspects, the malalignment of teeth may also cause ...
Eligibility Criteria
Inclusion
- 18 - 28 years old (M/F)
- Using orthodontic fixed appliance for at least 1 year
- Do not consume probiotics and antibiotics (at least 3 months before)
- No history of systemic disease
Exclusion
- Subjects with systemic diseases
- Allergic to probiotics
Key Trial Info
Start Date :
March 22 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2023
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT04847960
Start Date
March 22 2021
End Date
March 1 2023
Last Update
November 14 2022
Active Locations (1)
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1
Trisakti University
Jakarta, DKI Jakarta, Indonesia, 11440