Status:

COMPLETED

National Project on Vaccines, COVID-19 and Frail Patients

Lead Sponsor:

Azienda USL Reggio Emilia - IRCCS

Collaborating Sponsors:

Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

Istituto Clinico Humanitas

Conditions:

COVID-19

Solid Tumor

Eligibility:

All Genders

18+ years

Brief Summary

This is a multicentre observational study with the aim of evaluating the antibody and cellular response after vaccination for SARS-CoV-2 with Pfizer-BioNTech or Moderna vaccines in frail subjects with...

Detailed Description

The immune response to COVID-19 vaccination will be assessed at the following time points: T0: the day of vaccination T1: the day of the booster dose according to the schedule of the two vaccines (Pf...

Eligibility Criteria

Inclusion

  • Any subject undergoing SARS-CoV-2 vaccination with Pfizer-BioNTech or Moderna vaccines may be included in the study if they belong to at least one of the subgroups listed below:
  • Hematological tumors
  • Solid tumors
  • Rheumatological diseases
  • Neurological diseases

Exclusion

  • NA

Key Trial Info

Start Date :

April 19 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 31 2022

Estimated Enrollment :

747 Patients enrolled

Trial Details

Trial ID

NCT04848493

Start Date

April 19 2021

End Date

December 31 2022

Last Update

June 13 2025

Active Locations (12)

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Page 1 of 3 (12 locations)

1

IRCCS Istituto Tumori Giovanni Paolo II

Bari, Bari, Italy

2

IRCCS Azienda Ospedaliera Universitaria

Bologna, Bologhna, Italy

3

Ospedale Policlinico San Martino IRCCS

Genova, Genova, Italy

4

Foindazione IRCCS Istituto Neurologico Carlo Besta

Milan, Milano, Italy