Status:
RECRUITING
Cardiac Tissue Sodium Assessment in CKD Patients Using Sodium MRI
Lead Sponsor:
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Conditions:
Chronic Kidney Diseases
Dialysis; Complications
Eligibility:
All Genders
18+ years
Brief Summary
Chronic kidney disease (CKD) is prevalent worldwide and affects around 10% of people living in developed health economies. As the kidney loses its function in patients with CKD, the kidneys are unable...
Detailed Description
This study is a pilot exploratory study (preliminary project to assess the use of a heart sodium coil across a wide spectrum of kidney disease). We will recruit up to 150 participants: approximately 5...
Eligibility Criteria
Inclusion
- Age greater than or equal to 18 years
- For patients on maintenance hemodialysis: more than 3 months duration of therapy
- For patients with CKD: evidence of kidney disease persisting \> 3 months and no indications to start dialysis
- For healthy controls: lack of kidney disease, cardiovascular disease, diabetes, liver cirrhosis and peripheral edema
Exclusion
- Pregnant, breastfeeding or intending pregnancy
- Contraindication to MRI scan
- Inability to tolerate MRI due to patient size and/or known history of claustrophobia.
- Mechanically implanted, electrically, or magnetically activated device or any metal in their body which cannot be removed, including but not limited to pacemakers, neurostimulators, biostimulators, implanted insulin pumps, aneurysm clips, bioprosthesis, artificial limb, metallic fragment or foreign body, tattoos, shunt, surgical staples (including clips or metallic sutures and/or ear implants.)
Key Trial Info
Start Date :
July 10 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT04848636
Start Date
July 10 2022
End Date
December 31 2025
Last Update
July 24 2024
Active Locations (1)
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1
Victoria Hospital
London, Ontario, Canada, N6A5W9