Status:

UNKNOWN

Neurofeedback to Improve Spasticity After Incomplete Spinal Cord Injury

Lead Sponsor:

NHS Greater Glasgow and Clyde

Conditions:

Incomplete Spinal Cord Injury

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

After incomplete spinal cord injury (iSCI), many people still have control over their upper and/or lower limbs, but secondary conditions such as spasticity impair the function they have left. Spastici...

Detailed Description

The proposed study is a pilot exploratory study. It will be carried out on 20 chronic and sub-acute incomplete spinal cord injury participants who will receive five sessions of neurofeedback treatment...

Eligibility Criteria

Inclusion

  • Inclusion Criteria for subacute upper limb:
  • Aged above 18
  • Incomplete injury to the spinal cord, resulting in ASIA level C or D SCI
  • Injury occurred no more than six months prior to participation in the study
  • Injury level C3 to C7
  • Normal or corrected to normal vision
  • Spasticity equivalent of MAS level 1+ and above
  • Inclusion Criteria for chronic upper limb:
  • Aged above 18
  • Incomplete injury to the spinal cord, resulting in ASIA level C or D SCI
  • Injury occurred more than one year prior to participation in the study
  • Injury level C3 to C7
  • Normal or corrected to normal vision
  • Spasticity equivalent of MAS level 1+ and above
  • Live in Greater Glasgow and Clyde area
  • Inclusion Criteria for subacute lower limb:
  • Aged above 18
  • Incomplete injury to the spinal cord, resulting in ASIA level C or D SCI
  • Injury occurred no more than six months prior to participation in the study
  • Injury level T1 to L1
  • Normal or corrected to normal vision
  • Ability to walk \> 10 meters (assisted or unassisted), if ASIA level D
  • Spasticity equivalent of MAS level 1+ and above
  • Inclusion Criteria for chronic lower limb:
  • Aged above 18
  • Incomplete injury to the spinal cord, resulting in ASIA level C or D SCI
  • Injury occurred more than one year prior to participation in the study
  • Injury level T1 to L1
  • Normal or corrected to normal vision
  • Ability to walk \> 10 meters (assisted or unassisted), if ASIA level D
  • Spasticity equivalent of MAS level 1+ and above
  • Live in Greater Glasgow and Clyde area

Exclusion

  • Exclusion Criteria for subacute groups:
  • Participation in any other neurofeedback intervention group
  • Inability to understand the task
  • Self-reported neurological disorders e.g. previously confirmed peripheral nerve injury or brain injury
  • General poor health due to secondary consequences of injury
  • Conditions contra-indicative of neurostimulator usage (implanted devices, sensitive skin sores in the upper and lower extremities, pregnancy, severe autonomic dysreflexia)
  • History of epilepsy
  • Inability to sit for 1.5 hours
  • Inability to speak and/or understand English
  • Exclusion Criteria for chronic groups:
  • Participation in any other neurofeedback intervention group
  • Inability to understand the task
  • Self-reported neurological disorders e.g. previously confirmed peripheral nerve injury or brain injury
  • General poor health due to secondary consequences of injury
  • Conditions contra-indicative of neurostimulator usage (implanted devices, sensitive skin sores in the upper and lower extremities, pregnancy, severe autonomic dysreflexia)
  • History of epilepsy
  • Inability to sit for 1.5 hours
  • Inability to speak and/or understand English
  • Live outside Greater Glasgow and Clyde area

Key Trial Info

Start Date :

August 31 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2023

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT04849676

Start Date

August 31 2021

End Date

July 1 2023

Last Update

April 18 2022

Active Locations (1)

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1

Queen Elizabeth University Hospital, Queen Elizabeth National Spinal Injurie Unit

Glasgow, Glasgow City, United Kingdom, G51 4TF