Status:
UNKNOWN
Feasibility of Tracheobronchial Reconstruction Using Bioengineered Aortic Matrices
Lead Sponsor:
National Taiwan University Hospital
Conditions:
Trachea Diseases
Tracheal Stenosis
Eligibility:
All Genders
20+ years
Phase:
NA
Brief Summary
We used a segment of cryopreserved aorta as a graft for reconstruction for long segment tracheobronchial lesion in human.
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Patients with advanced benign or malignant lesions involving trachea or bronchi, and has failed conventional treatment.
- Patients with proximal pulmonary tumors that require surgical resection and has involved proximal airways which is indicated for a pneumonectomy, sleeve lobectomy, or carina resection.
- Exclusion criteria:
- Less than 20-year-old
- Unable to obtain informed consent.
- Pulmonary tumors that can be treated with standard lobectomy.
- Unresectable locally advanced malignant tumors
- Malignant tumors with contralateral lymph nodes involvement.
- Malignant tumors with distal metastases; except for simple resectable brain metastasis.
- Tracheal lesions which can be treated with standard resection and direct anastomosis.
- Allergic to iodine
- Unable to tolerate standard lobectomy
- Has human immunodeficiency virus infection
- Tracheal stenosis at proximal 2 cm on upper trachea
Exclusion
Key Trial Info
Start Date :
January 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2024
Estimated Enrollment :
5 Patients enrolled
Trial Details
Trial ID
NCT04850742
Start Date
January 1 2019
End Date
March 1 2024
Last Update
May 11 2021
Active Locations (1)
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1
National Taiwan University Hospital
Taipei, Taiwan, 100