Status:
RECRUITING
Neural Mechanisms of Immersive Virtual Reality in Chronic Pain
Lead Sponsor:
University of Maryland, Baltimore
Conditions:
Pain
Virtual Reality
Eligibility:
All Genders
18-88 years
Phase:
PHASE1
PHASE2
Brief Summary
This project examines, in chronic pain, the mechanisms of immersive virtual reality compared to the mechanisms of placebo hypoalgesia. The potential of developing new non-pharmacological premises for ...
Detailed Description
Virtual reality (VR) has been seen as an intervention for alleviating clinical chronic (and acute) pain. An approach to pain management utilizing VR presents opportunities for reducing pain and suffer...
Eligibility Criteria
Inclusion
- Age (18-88 years)
- English speaker (written and spoken)
- Temporal Mandibular Disorder (TMD) for at least 3 months
Exclusion
- Present or past degenerative neuromuscular disease
- Cardiovascular, neurological diseases, pulmonary abnormalities, kidney disease, liver disease, history of cancer within past 3 years
- Cervical pain other than TMD related (e.g. stenosis, radiculopathy)
- Any personal (or family first degree) history of mania, schizophrenia, or other psychoses
- Severe psychiatric condition (e.g., schizophrenia, bipolar disorders, autism) leading to hospitalization within the last 3 years.
- Use of antidepressants, ADHD medication, non-over-the-counter painkillers, methadone, benzodiazepines, barbiturates, and/or narcotics during the past 3 months
- Lifetime alcohol/drug dependence or alcohol/drug abuse in the past 3 months
- Pregnancy or breastfeeding
- Color-blindness
- Pain in jaw or temple in last 3 months due to toothache or infection
- Any facial trauma that has occurred in the last 6 weeks
- History of severe facial trauma in the last 3 months
- Impaired or uncorrected hearing
- Conditions that would interfere with the VR mask placement (e.g. trauma, burn, infection)
- Known history of severe motion sickness
- High blood pressure or symptomatic low blood pressure
- History of fainting
- History of angioedema
- Failed drug test (testing for opiates, cocaine, methamphetamines, amphetamines, and THC)
Key Trial Info
Start Date :
November 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 30 2026
Estimated Enrollment :
259 Patients enrolled
Trial Details
Trial ID
NCT04851301
Start Date
November 1 2021
End Date
November 30 2026
Last Update
June 25 2025
Active Locations (1)
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1
Luana Colloca
Baltimore, Maryland, United States, 21201-1512